About the LabPartners Team
Team leads (Dr. Manoj Lalu, Ottawa Hospital Research Institute, University of Ottawa; Dr. Dean Fergusson, Ottawa Hospital Research Institute, University of Ottawa; Dr. Dawn Richards, Five02 Labs Inc.) have assembled an interdisciplinary team composed of patient partners, preclinical researchers, clinical researchers, clinician-scientists, and highly qualified personnel who have extensive experience with patient engagement and/or preclinical research. Our team also encompasses team members from the Ottawa Methods Centre’s Office for Patient Engagement in Research Activities (OPERA).
Click on Photos and Bios to Learn More.
Manoj Lalu
Researcher
Biography
Dr. Lalu is an Anesthesiologist at The Ottawa Hospital and a Scientist at the OHRI (Clinical Epidemiology and Regenerative Medicine Programs). He is an Associate Professor in uOttawa’s Department of Anesthesiology and Pain Medicine with a cross-appointment in the Department of Cellular and Molecular Medicine. His current interests revolve around improving the preclinical to clinical translational pathway. This includes conducting preclinical and clinical systematic reviews, as well as meta-research on the conduct and reporting of laboratory-based studies. He co-supervises dry-lab projects. In addition, his wet lab is currently conducting multi-centre preclinical studies, and investigating extracellular vesicles in sepsis and lung injury using murine models.
Dean Fergusson
Researcher
Biography
Dr. Dean Fergusson, PhD is a Senior Scientist and Director of the Clinical Epidemiology Program (CEP) at the Ottawa Hospital Research Institute and a Full Professor in the Department of Medicine with cross-appointments to the School of Epidemiology & Public Health and the Department of Surgery at the University of Ottawa. His two areas of research scholarship are: 1) transfusion medicine and transfusion alternatives; and 2) innovative methodological research into the design and analysis of clinical trials. His methodological work in clinical trials includes the areas of clinical equipoise, innovative pragmatic trials, patient and public engagement, post-randomization exclusions, ethical use of placebo controls, and statistical approaches.
Dawn Richards
Patient Partner
Biography
Dawn Richards, PhD, is the founder of Five02 Labs Inc. Her firm manages projects; prepares and writes grant, manuscript, and lay language materials; and helps bring patient and community member
perspectives to research and healthcare spaces. With a PhD (Analytical Chemistry) from the University of Alberta, Dawn has worked in a variety of roles during the past 20 years, however her diagnosis with rheumatoid arthritis almost 15 years ago began her journey to combine her passion for science with making the most of her diagnosis. Dawn is the volunteer Vice President of the Canadian Arthritis Patient Alliance, a patient led and run organization.
Angela M. Crawley
Researcher
Biography
Angela is a Senior Scientist in the Chronic Disease Program in The Ottawa Hospital Research Institute. She is also an Associate Professor (awaiting final approval) in the Department of Biochemistry, Microbiology and Immunology with the University of Ottawa, and an Adjunct Professor at Carleton University. A wet-lab basic science researcher in immunology, Angela is focused on the study of how chronic liver disease influences the immune system, particularly in hepatitis C virus infection and metabolic fatty liver disease largely in human specimens and more recently using mouse models. Angela chairs the Ottawa Viral and Metabolic Liver Disease Research Group and is an active member of several national research communities in liver diseases. She also conducts immunology research on Covid-19 and is the Biobank Director for the CIHR funded Coronavirus Variants Rapid Response Network (CoVaRR-Net), and currently trailblazing a sustainability effort for this network as THE pandemic preparedness academic research hub for Canada. Angela’s research program is translational by design, fortified by her extensive record of successful, long-term research collaborations with clinicians that benefit her research program and has contributed to several clinical trials and studies locally, nationally and internationally.
Kirsten Fiest
Researcher
Biography
Kirsten is an Associate Professor of Critical Care Medicine, Community Health Sciences & Psychiatry at the University of Calgary. She is also Director of Research and Innovation in the Department of Critical Care Medicine. Kirsten received her PhD in Epidemiology from the University of Calgary and completed post-doctoral training in neuro and psychiatric epidemiology from the University of Manitoba. Her research program focuses on advancing the science of patient and family-centered critical care research. Her current work examines the role of family in preventing, detecting, and managing delirium in the critically ill. Kirsten also teaches Introduction to Epidemiology in the Department of Community Health Sciences graduate program.
Kathryn Hendrick
Patient Partner
Biography
Kathryn Hendrick is a veteran health communications specialist and the primary caregiver for her father who passed away recently from sepsis. She saw firsthand how important it is to recognize and manage sepsis when it strikes, and yet how variable the standard of care can be in a home care setting and a hospital. She is now a patient representative for the Canadian Sepsis Network.During the last two years of his life, Kathryn accompanied her father on several hospital admissions through emergency and week-long inpatient stays. She realized that depending on the hospital and their sepsis management protocols, treatment was never the same in any two places. After each subsequent sepsis admission, almost at six-week intervals and which on two occasions advanced to septic shock, her father became progressively weaker and despondent. As a health care publicist, Kathryn has worked in academic hospitals across Canada as a senior executive leading the public affairs and advocacy portfolios. In this role, she was responsible for promoting major research breakthroughs in cardiovascular disease, critical care, infectious diseases, psychiatry, and other areas, but never sepsis — despite its prevalence.In her role as a patient representative, Kathryn hopes to see advances in the diagnosis, treatment, and management of sepsis patients. Her hope is that the Sepsis Network will one day address the many gaps in care, but also in training, education, and research.
Kimberly Macala
Researcher
Biography
Dr. Kimberly Macala is an Assistant Professor in the Department of Critical Care Medicine at the University of Alberta, an Intensivist and Anesthesiologist at the Royal Alexandra Hospital in Edmonton, Alberta, and is completing a PhD in Experimental Surgery in association with an expanding research program focusing on sepsis in the neonatal and elderly critically ill population at the University of Alberta. She initially completed her BSc with Great Distinction in Physiology in 2003 and went onto graduate with her Medical Doctorate in 2008, both at the University of Saskatchewan. She subsequently completed her residency in Anesthesiology and Pain Medicine at Memorial University of Newfoundland in 2013 and a fellowship in Adult Critical Care Medicine in 2015 with further training through the Royal College Clinician Investigator Program in 2017 at the University of Alberta.
Asher Mendelson
Researcher
Biography
Dr. Asher Mendelson is a Clinician-Scientist in the Section of Critical Care Medicine, Department of Medicine, Rady Faculty of Health Sciences at the University of Manitoba. The focus of Dr. Mendelson’s research program is microvascular physiology in sepsis and critical illness. He is the project co-lead for the National Preclinical Sepsis Platform: a multicentre preclinical trial within the CIHR-funded Sepsis Canada Research Network. At the bedside, he is developing advanced biomedical optics and signals analysis tools to monitor microvascular oxygen delivery and perfusion with the goal to improve the diagnosis and management of cardiovascular failure. His research program is funded by the Winnipeg Foundation, Cardiac Sciences Program, and the Rady Faculty of Health Sciences. Dr. Mendelson is an active member of the Canadian Critical Care Translational Biology Group.
Pat Messner
Patient Partner
Biography
Pat has a varied background becoming a World Champion Athlete and the only Canadian to have an Olympic Medal in the sport of water skiing. She was given the Order of Canada becoming the youngest female at that time. After retiring she became a Paramedic and worked as a percussionist with the National Arts Center Orchestra. When her water ski injuries caught up with her she finished her BA and then a BEd. She worked as a Head Teacher in an Alternative HighSchool till retirement. Meanwhile her body gave out and she underwent over fifty surgeries and has become the bionic woman. As a Patient Advisor she now is the Chair of the CPDMH PFAC, works with TOH on healthcare education, is on the CCHCE Ethics committee, the OODO Advisory Group as well as the Champlain Medical Imaging Network Steering Co. She also works with various groups on the science of health care, trying to make the world of medicine a little less scary and more patient oriented. In her spare time, she continues to coach and to work with several orchestras and bands.
Stuart Nicholls
Researcher
Biography
Dr. Stuart Nicholls is the Strategy for Patient-Oriented Research (SPOR) Program Facilitator in the Office for Patient Engagement in Research Activities (OPERA) at the Ottawa Methods Centre. In his capacity as SPOR Program facilitator he consults with researchers to provide methodological guidance regarding all aspects of Patient-Oriented Research. In addition, he provides training and education on patient engagement in research and actively contributes to research in this field. His research includes exploration of parent experiences of consent, public attitudes to genomics, and work to explore the impact of patient engagement on research. Dr. Nicholls was a member of the Canadian Clinical Trials Coordinating Centre (CCTCC)/Health Canada working group on developing a pan-Canadian accreditation system for Research Ethics Boards reviewing clinical trials. He is also a member of the Health Canada/Public Health Agency of Canada Research Ethics Board.
Justin Presseau
Researcher
Biography
Dr. Presseau is a Scientist at the Ottawa Hospital Research Institute and Associate Professor in the School of Epidemiology & Public Health and School of Psychology at the University of Ottawa. He leads the Psychology and Health Research Group (PaHRG) and is a core faculty member of the Centre for Implementation Research at the Ottawa Hospital. He holds a Ph.D. in Psychology from the University of Aberdeen (UK). His research program operates at the intersection between health psychology and implementation science, focusing on developing and evaluate interventions to support changing healthcare professional behaviours and health behaviours of patients and the public.
Cheryle A. Séguin
Researcher
Biography
Dr Séguin is a Professor in the Department of Physiology and Pharmacology in the Schulich School of Medicine & Dentistry at the University of Western Ontario. Since her recruitment in 2009, Dr. Séguin has established an internationally recognized research program focused on intervertebral disc biology and disease. Research led by her group has used transgenic mouse models to investigate progenitor cell types in intervertebral disc development and better understand the cellular changes associated with common spine disorders such as intervertebral disc degeneration and diffuse idiopathic skeletal hyperostosis. She is the former recipient of New Investigator Award from the CIHR and is currently supported by a career Development award from the CIHR/Arthritis Society. Dr. Séguin has made important contributions to graduate training, contributing to the establishment and currently serving as co-Director of the Collaborative Specialization in Musculoskeletal Health Research at Western, in addition to former roles in training and Education with the Ontario Institute of Regenerative Medicine and Stem Cell Network.
Patrick J. Sullivan
Patient Partner
Biography
Patrick Sullivan is a passionate childhood cancer advocate, and Chair of the Board of Childhood Cancer Canada and one of the founders of the Team Finn Foundation. Patrick became an advocate after his twin son Finn was diagnosed with Rhabdomyosarcoma in 2007 and heard the word “incurable” for the first time in May 2008. His desire to make a change in cancer research is in part an effort to pay an un-payable debt to his son Finn and to change the stories of other Finn’s. Patrick participates in several
national and international initiatives that include one of the founders of Ac2orn (Advocacy for Canadian Children Oncology Research Network), a director of the CCRA, member of the executive of the Terry Fox Research Profile initiative, member of the AACR Pediatric Cancer Working Group and Chair of the St. Baldrick’s/Stand-Up to Cancer Immunogenomics Advocates Dream Team. By profession, Patrick is a securities and corporate-commercial litigator practicing at Whitelaw Twining. Patrick is the proud father of three remarkable children, Baird, Sarah and Finn and would do almost anything for the simple pleasure of holding Finn’s hand again.
Bernard Thébaud
Researcher
Biography
Dr. Bernard Thébaud is a clinician-scientist with a focus on the clinical translation of stem cell-based and gene therapies for lung diseases. He is a Senior Scientist with the Ottawa Hospital Research Institute and a Neonatologist with the Children’s Hospital of Eastern Ontario, providing care to critically ill newborns. He is also a Professor of Pediatrics at the University of Ottawa. Dr. Thébaud holds the University of Ottawa Partnership Research Chair in Regenerative Medicine. Dr. Thébaud obtained his MD at the University Louis Pasteur in France and trained in Pediatrics and Neonatology at the University Paris V, where he obtained his MSc and PhD, before completing a 2-year postdoctoral fellowship at the University of Alberta. Dr. Thébaud studies the mechanisms of lung development, injury and repair to design new treatments for incurable lung diseases. His focus is on answering clinically relevant questions for translation into real-life applications. Over the next five years, his goal is to bring safe and effective cell and gene therapies for lung diseases into the clinic to improve patient outcomes. Dr. Thébaud participates on numerous peer review committees and scientific advisory boards at the international, national and provincial level, including CIHR and NIH. His research is funded by the Canadian Institutes of Health Research, the Heart and Stroke Foundation of Canada, and the Stem Cell Network.
Madison Foster
Researcher
Biography
Madison is a Project Manager working with the Blueprint Translational Research Group, led by Dr. Manoj Lalu and Dr. Dean Fergusson at the Ottawa Hospital Research Institute (OHRI). Madison’s current research focuses on studying and facilitating patient engagement (involving patients and caregivers as collaborators throughout the research process). Through this work the team aims to better align their research with patient priorities and interests, as well as create guidance for patient engagement. Madison will be helping to facilitate the Patent Engagement in Basic Science program. Previously, she completed a BSc in Biopharmaceutical Sciences and an MSc in Epidemiology, both at the University of Ottawa.
Meredith Conboy
Highly Qualified Personnel
Biography
Meredith primarily works on Cellular precOnditioning for post-Surgical Myocardial Ischemic Complications (COSMIC), a phase I clinical trial that aims to test the safety and feasibility of using mesenchymal stromal cells (MSCs) as a preconditioning treatment for perioperative cardiac complications. She also works on some of the team’s Patient Engagement programs, which focus on facilitating patient engagement in preclinical laboratory research (LabPartners) and very early phase clinical trials (MARVEL).
Grace Fox
Highly Qualified Personnel
Biography
Grace worked as a summer student, research assistant and graduate student for the Blueprint Translational research group. She recently finished her MSc in Epidemiology at the University of Ottawa and has taken on a new role at the Ottawa Methods Center where she helps researchers and patient advisors navigate patient engagement in research. Grace’s research interests include patient engagement along the research continuum. She also worked on a clinical trial focused on virtual care as a method of monitoring recovery at home after surgery. Grace focused her MSc thesis on patient partner recognition, specifically financial compensation.
Talston Scott
Highly Qualified Personnel
Biography
Talston is a clinical research assistant working with the Blueprint Translational Research Group at the Ottawa Hospital Research Institute. He is primarily involved in the LabPartners project, which focuses on patient engagement in preclinical laboratory research. Prior to joining the Blueprint Group, Talston completed a Bachelor of Health Sciences (Honours) concentrating in Global Health at Carleton University before obtaining a Masters Degree in Health Ethics from Memorial University of Newfoundland.
Emma Gerber
PhD Candidate
Biography
Emma is a PhD Candidate in the labs of Dr. Benjamin Tsang and Dr. Dylan Burger at the Ottawa Hospital Research Institute. Her research focuses on understanding the molecular basis of chemoresistance in epithelial ovarian cancer and identifying biomarkers to predict whether patients will respond to chemotherapy. Emma is inspired by work in collaboration with ovarian cancer patient partners and hopes to inspire the next generation of cancer researchers through community outreach with elementary and high school students.